適用對象(Availiability)
大學部 1年級至7年級
上課時間(Crouse Load)
2022/08/01~
課程概述(Crouse Description)
本課程以全英語授課，將選取日常生活事務，包括營養、健康、醫藥、科技等有趣的議題，導引學生建立最重要的生物化學觀念及其觀念之整合。除了課前講義、模型或影片等多媒體教材，並運用課前練習及IRS互動系統，增進與學生間互動及討論，即時了解學生學習狀況。希望藉由此課程，培養同學的科學素養、溝通能力、對專業科目英語字彙及專業知識的累積。 This course is taught in English. Perfect English proficiency is not necessarily required for this class, but the brave and prepared spirit that is willing to take the challenge of discussing in English is mandatory. The course is aimed to build up the fundamental concepts of biochemistry and integrate these concepts. Fun topics from our daily life, including food, health, medicine, biotechnology that are related to biochemistry will be chosen for discussion. Through the topics, we hope to inspire students and made them engaged in learning. Except handouts, multimedia (animation, computer modeling and videos) and pre-lecture exercise will be posted online before each class. IRS (immediate response system) and group discussion will be implemented in classroom. Upon completion, students should have a mental model of the basic components found in organisms, such as food we eat, as well as how these components function in our body. In addition, students will learn relevant English medical terminology and feel more comfortable using English in scientific discussion and presentation.
教學目標(Crouse Objectives)
在完成本學期的課程之後，學生們應能 1. 認識主要的生物分子的種類、化學性質、構造及其生物功能。 2. 了解基本生物分子的新陳代謝與能量的轉換利用，並了解能量與代謝整合調節的重要性。 3. 說明遺傳訊息表現的分子基礎及其調控。 4. 運用建立的基本生化觀念探討相關疾病、醫藥或生物科技的發展與應用 5. 增進專業科目英語字彙的能力，並學習如何以英文討論科學專業議題及報告This is an introductory course to provide the fundamental understandings of life. The intention of the course is for students to (1) know the composition, structure and function correlation of the major classes of biological molecules. (2) understand the principles of metabolic pathways including: enzyme function, chemical conversion and bioenergetics of biomolecules, integration and regulation, and recognize how improper regulation of these biochemical processes can lead to human disease. (3) understand the molecular processes and regulation in expressing genetic information. (4) allow students to further understand and analyze biochemical aspects of relevant diseases, medicine, and biotechnology. (5) know relevant English medical terminology and improve the English proficiency in scientific discussion/ presentation
先修科目(Prerequisites)
高中生物及化學 High school Biology and Chemistry
每週進度(Schedule)
2022/OO/OO第一週 Introduction: Biochemistry and you (A briefreview of biomolecules) Introduction: Biochemistry and you (A brief review of biomolecules)李妙蓉(Miau-Rong Lee)
2022/OO/OO第二週 What happens when you add lemon juice to milk? How do proteins get their shapes? (Amino acids, protein structure and function) What happens when you add lemon juice to milk? How do proteins get their shapes? (Amino acids, protein structure and function)李妙蓉(Miau-Rong Lee)
2022/OO/OO第三週 What does Beano do? Why do you take penicillin? (Enzymes ) What does Beano do? Why do you take penicillin? (Enzymes )李妙蓉(Miau-Rong Lee)
2022/OO/OO 第四週 Why do you need vitamins? Why do you need vitamins?鄭雅興(Cheng, YaHsin)
2022/OO/OO 第五週 What's the difference between milk sugar and table sugar? (Carbohydrate structure) How does your body produce energy from food? (Metabolism overview) What's the difference between milk sugar and table sugar? (Carbohydrate structure) How does your body produce energy from food? (Metabolism overview)李妙蓉(Miau-Rong Lee)
2022/OO/OO 第六週 Why do you exhale carbon dioxide? (TCA cycle) Why must you breathe in oxygen? (ETC) What happens when you eat sugar? (Glycolysis) Why do you exhale carbon dioxide? (TCA cycle) Why must you breathe in oxygen? (ETC) What happens when you eat sugar? (Glycolysis)林靜茹(Chingju Lin)
2022/OO/OO 第七週 Can your body store and make sugar? (Carbohydrate metabolism: gluconeogenesis, pentose phosphate pathway, glycogenesis &glycogenolysis) Can your body store and make sugar? (Carbohydrate metabolism: gluconeogenesis, pentose phosphate pathway, glycogenesis &glycogenolysis)李妙蓉(Miau-Rong Lee)
2022/OO/OO 第八週 Midterm Exam Week Midterm Exam Week林靜茹(Chingju Lin)
2022/OO/OO 第九週 Fats: friend or foe? (Lipid) What happens when you eat fats? (lipid digestion, beta-oxidation) Fats: friend or foe? (Lipid) What happens when you eat fats? (lipid digestion, beta-oxidation)林靜茹(Chingju Lin)
2022/OO/OO 第十週 Can your body make fat from sugar? (Lipid metabolism) Why are some amino acids essential? Do you need to eat DNA? (Nitrogen metabolism) Can your body make fat from sugar? (Lipid metabolism) Why are some amino acids essential? Do you need to eat DNA? (Nitrogen metabolism)李妙蓉(Miau-Rong Lee)
2022/OO/OO 第十一週 Metabolic Integration: nutrition (Insulin and low-carbohydrate diets) Metabolic Integration: nutrition (Insulin and low-carbohydrate diets)鄭雅興(Cheng, YaHsin)
2022/OO/OO 第十二週 Metabolic Integration: Exercise and energy metabolism Metabolic Integration: Exercise and energy metabolism林靜茹(Chingju Lin)
2022/OO/OO 第十三週 Case study (Alcohol consumption and addition) Case study (Alcohol consumption and addition)李妙蓉(Miau-Rong Lee)
2022/OO/OO 第十四週 Is making a precise copy of cellular DNA essential? How genes are “turn on”? How does your body make proteins? (Nucleic acid and protein synthesis) Is making a precise copy of cellular DNA essential? How genes are “turn on”? How does your body make proteins? (Nucleic acid and protein synthesis)李妙蓉(Miau-Rong Lee)
2022/OO/OO 第十五週 Oral presentation Oral presentation鄭雅興(Cheng, YaHsin)
2022/OO/OO 第十六週 Simple animal, big picture of life (Gene transfer and Biotechnology) Simple animal, big picture of life (Gene transfer and Biotechnology)李妙蓉(Miau-Rong Lee)
2022/OO/OO 第十七週 期末考 Final Exam鄭雅興(Cheng, YaHsin)
教學方式(Teaching Methods)
線上講課Online Lecturing 小組討論Online Group discussion 學生上台報告Online Oral presentation 腦力激盪Brain storming 習題練習Exercise 影片欣賞與討論Movie review and discussions 翻轉教學Flipped classroom
評量方式(Assessment)
線上期中筆試Online Midterm exam 線上隨堂筆試測驗 Online In-class exam 線上期末筆試 Online Final exam 小組作業 Group homework 線上期末報告Online Final report 線上出席狀況 Online Class attendance 線上課堂參與與表現 Online Class involvement
修習學分(Credits)
學分
參考書目(Reference)
1.Lippincott’s Illustrated Reviews: Biochemistry, 6th ed., 2014, Denise R. Ferrier, (Wolters Kluwer/Lippincott, Williams & Wilkins), [ISBN: 978-1-4511-7562-2] 2. Chemistry: Introduction to General, Organic & Biological Chemistry, 11th ed., 2012, Karen C.Timberlake, (Pearson) [ISBN-10: 0-321- 72782-7, ISBN-13: 978-0-321-72782-7]
